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Audio Interchange File Format  |  1996-11-08  |  396.5 KB  |  1 channel  |  11,025 sample rate  |  18 seconds
Transcription: Dose limiting. A side effect, complication or risk that makes it impossible or unwise to exceed a specific dose of a chemotherapeutic agent. A total dosage of bleomycin of more than 400 units, for example, may produce severe lung scarring. Lung toxicity is, therefore, dose limiting.